The successful optimization of a maintenance schedule, which represents one of the Runner most important operational measures for the reduction of fuel consumption and greenhouse gas emission, relies on accurate prediction of the impact of cleaning on the ship performance.The impact of cleaning can be considered through the impact of biofouling on
IntroductionTherapies for Leber hereditary optic neuropathy (LHON), in common with all disorders caused by mutated mitochondrial DNA, are inadequate.We have developed two gene therapy strategies for the disease: mitochondrial-targeted and allotopic expressed and compared them in a mouse model of LHON.MethodsA LHON mouse model was generated by intra
Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, accounting for the majority of breast cancer-related death.Due to the lack of specific therapeutic targets, chemotherapeutic agents (e.g., paclitaxel) remain the mainstay of systemic treatment, but enrich a subpopulation of cells with tumor-initiating cap
Enhancement of vessel detection performance in synthetic aperture radar (SAR) images generated academic advancements related to amelioration of the algorithmic accuracy and training data procurement.For practical implementation of vessel detection algorithm to maritime surveillance, however, presentation of authentic position of EYE PRO vessels was
Background Digital health technology (DHT) has become an essential part of an effective and efficient healthcare information system.Although DHT promises great potential it does not always meet the expectation of users.Often, in low- and middle-income countries (LMICs), the implemented DHT does not function as intended and impacts negatively on hea